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MODULE DESCRIPTOR
Module Title
Clinical Immunology
Reference PL3901 Version 2
Created September 2023 SCQF Level SCQF 9
Approved June 2023 SCQF Points 15
Amended September 2023 ECTS Points 7.5

Aims of Module
To provide students with the ability to discuss the molecular and cellular basis of diseases affecting the immune system, and the applications of immunological techniques designed to diagnose and monitor them.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Discuss lymphocyte activation and control, and the interaction of the immune system with antigen.
2 Explain the immunology of hypersensitivity, autoimmunity, immunodeficiency, transplantation and cancer.
3 Demonstrate knowledge and understanding of the features and applications of immunoassays in the diagnosis and monitoring of diseases affecting the immune system.

Indicative Module Content
Lymphocyte Activation & Control: first and second signals, accessory molecules, soluble immunoregulators (cytokines, interleukins, chemokines).Defence against Infection: vaccination, subversion by pathogens, superantigens. Hypersensitivity : types I to V. Autoimmunity: MHC, rheumatological (SLE, RA, autoantibodies) and kidney(Goodpastures) and organ-specific (thyroid, coeliac, pernicious anaemia, diabetes) diseases. Immunodeficiency: Complement, primary (T & B & NK cell) and secondary (HIV). Transplantation: rejection, solid organs, bone marrow. Cancer : tumour antigens, evasion. Immunoassays: haemagglutination, RIA, ELISA, tissue typing, functional assays.

Module Delivery
This is a lecture based module supplemented by tutorials and group discussions.

Indicative Student Workload Full Time Part Time
Contact Hours 40 N/A
Non-Contact Hours 110 N/A
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 150 N/A
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Examination Weighting: 70% Outcomes Assessed: 1, 2
Description: Extended response questions
Component 2
Type: Coursework Weighting: 30% Outcomes Assessed: 3
Description: Problem solving exercise

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
The first grade represents Component 1 (EX1) and is weighted as major. A minimum of grade D is required to pass this component of assessment. The second grade, Component 2 (CW1), is weighted as minor. A minimum of grade D is required to pass this component of assessment. A minimum of Module Grade D is required to pass the module. Non-submission of either component will result in an NS grade.
Module Grade Minimum Requirements to achieve Module Grade:
A AA, AB
B AC, AD, BA, BB, BC, CA
C BD, CB, CC, CD, DA, DB
D DC, DD
E AE, AF, BE, BF, CE, CF, DE, DF, EA, EB, EC, ED, EE, EF, FA, FB, FC, FD
F FE, FF
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module Successful completion of Stage 2 of the course, or equivalent.
Corequisites for module None.
Precluded Modules None.

ADDITIONAL NOTES
In accordance with the BSc (Hons) Biomedical Science/BSc (Hons) Applied Biomedical Science Course Specification and IBMS Criteria and Requirements for Degree Accreditation Criteria 4.2 (v), students must achieve a pass mark in all assessment components for modules that cover the clinical laboratory sciences subject areas.

INDICATIVE BIBLIOGRAPHY
1 Murphy, K, Weaver, C, Berg, L.J. Janeway's Immunobiology Tenth International Student Edition, 2022, Norton and Company
2 DELVES, P.J., MARTIN, S.J., BURTON, D.R and ROITT, I.M. Roitt's Essential Immunology. 13th Edition, 2017: Wiley-Blackwell Publishing.

Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781