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MODULE DESCRIPTOR
Module Title
Medicine Design And Manufacture
Reference PL2003 Version 1
Created April 2022 SCQF Level SCQF 8
Approved June 2022 SCQF Points 30
Amended August 2021 ECTS Points 15

Aims of Module
To develop an understanding of the design of safe and effective medicines within a quality framework in the context of a variety of patient groups.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Describe the process of medicine development from the raw active pharmaceutical ingredient (drug) to the final marketed product.
2 Discuss the principles involved in the design of quality medicinal products and devices, their packaging and stability assessment.
3 Explain how the design of a medicinal product affects drug absorption.
4 Critically evaluate the formulation of medicinal products taking into account factors relating to: the active pharmaceutical ingredient(s), any excipients, target patient groups, the conditions being treated, the indications for the active pharmaceutical ingredient(s).

Indicative Module Content
How to design safe and effective medicines for a variety of patient groups, utilising physicochemical data and the intended route of administration to develop commonly used dosage forms including tablets, capsules and liquids. Topics include: how active pharmaceutical ingredients become medicines and the stages involved from a product development viewpoint; factors influencing design of medicines; formulation principles relating to various basic dosage forms; stability and packaging of medicines; quality assurance principles and procedures; drug release from medicines; physiological factors affecting drug absorption; physicochemical characteristics of the drug and the dosage form being administered.

Module Delivery
Lectures, coursework sessions (including laboratory and non-laboratory based exercises & tutorials) and directed study.

Indicative Student Workload Full Time Part Time
Contact Hours 75 N/A
Non-Contact Hours 225 N/A
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 300 N/A
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Examination Weighting: 50% Outcomes Assessed: 1, 3
Description: Closed book written examination
Component 2
Type: Coursework Weighting: 50% Outcomes Assessed: 2, 4
Description: Group based scientific report

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
Component 1 (EX1) comprises 50% of the module grade. A minimum of a Grade D or better is required to pass this assessment. Component 2 (CW1) comprises 50% of the module grade. A minimum of a Grade D or better is required to pass this assessment. Overall Grade D or better is required to pass this module. Non-submission of either component will result in an NS grade for the module.
Examination:
Coursework: A B C D E F NS
A A A B B E E
B A B B C E E
C B B C C E E
D B C C D E E
E E E E E E F
F E E E E F F
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module Successful completion of MPharm Stage 1 or equivalent.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 AULTON, M.E. ed., 2022. Aulton's Pharmaceutics: The Design and Manufacture of Medicines. Sixth edition. Edinburgh: Churchill Livingstone.
2 ALLEN, L.V., POPOVICH, N.G. and ANSEL, H.C.. 2011. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. Ninth edition. Philadelphia: Lippincott Williams & Watkins.
3 FLORENCE, A.T. and ATTWOOD, D., 2016. Physicochemical Principles of Pharmacy. Sixth edition. London: Pharmaceutical Press.
4 MOYNIHAN, H. & CREAN, A., 2009. The Physicochemical Basis of Pharmaceuticals. First edition. Oxford: Oxford University Press.

Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781