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MODULE DESCRIPTOR
Module Title
Advanced Therapeutics and Personalised Medicine
Reference PHM045 Version 3
Created August 2021 SCQF Level SCQF 11
Approved May 2018 SCQF Points 15
Amended September 2021 ECTS Points 7.5

Aims of Module
To develop an understanding of the techniques pertinent to advanced drug delivery, gene technology, pharmacogenomics and proteomics and the ability to evaluate their application to the improved efficacy and safety of medicinal products.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Integrate knowledge of gene structure and function to explore how genomic, proteomic and metabolomic derived biomarkers can be used to progress personalised medicine.
2 Critically appraise how currently established targeted molecular and biological markers of disease and drug targets may be used in clinical practice.
3 Critically appraise novel stratified medicine to explore its advantages and disadvantages in clinical practice.
4 Critically reflect on ethical issues that may arise from the use of personalised medicine.

Indicative Module Content
Delivering advanced therapeutics solutions to achieve personalised medicines that are: right for the patient, safe, painless, reliable, targeted and efficient. Topics include: production of recombinant DNA and genetically engineered medicines, principles and applications of gene therapy, role of pharmacogenomics in the delivery of personalised medicine, genomic, proteomic and metabolomic screening for disease diagnosis and identification of drug targets, mechanism of action and use of immunotherapies, potential future technologies. Ethical issues that may arise from the use of novel technologies for medicine design and delivery.

Module Delivery
Online lectures (including delivery by external experts), online resources and discussions, directed study, self-assessment with answers and problem solving. There is no face-to-face contact required for this online module. 'Contact' hours included in 'Indicative Workload' represent online discussions and other online interactions.

Indicative Student Workload Full Time Part Time
Contact Hours N/A 10
Non-Contact Hours N/A 140
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL N/A 150
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Coursework Weighting: 100% Outcomes Assessed: 1, 2, 3
Description: Component 1 is a written assignment, Marked, 100% weighting.
Component 2
Type: Coursework Weighting: 0% Outcomes Assessed: 4
Description: Component 2 is a posting and participation in a discussion forum. Assessed on a Pass/fail basis.

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
A minimum module grade D is required to pass.
Module Grade Minimum Requirements to achieve Module Grade:
A When C1 = A and C2 is passed.
B When C1 = B and C2 is passed.
C When C1 = C and C2 is passed.
D When C1 = D and C2 is passed.
E When C1 = E and C2 is passed.
F When C1 = F AND/OR C2 is failed.
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module An undergraduate degree in a pharmacy, medical or nursing & midwifery related field from a UK university or overseas equivalent, and one year post-registration experience or in consultation with the Course Leader.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 TURNER, P.C., MCLENNAN, A.G., BATES, A.D. and WHITE, M.R.H. 2005. Instant Notes: Molecular Biology. Hoboken : Taylor & Francis.
2 Cullis P & Mehta A. 2015. Personalised Medicine Revolution: How Diagnosing and Treating Disease Are About to Change Forever. Saraband.
3 Padmanabhan S. 2014. Handbook of Pharmacogenomics and Stratified Medicine.London. Academic Press.

Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781