Prerequisites for Module
None, in addition to course entry requirements.
Corequisite Modules
None.
Precluded Modules
None.
Aims of Module
To enable students to critically appraise the design of drug delivery systems and development techniques.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Critically evaluate the design of drug delivery systems for various routes of administration.
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| 2. |
critically evaluate selected techniques used in the development of drug delivery systems.
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| 3. |
discuss current trends in drug targeting, biotechnology products and modified release drug delivery
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| 4. |
identify and resolve technological and documented problems associated with the development of drug delivery systems.
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| 5. |
work effectively in groups and to communicate scientific results in written reports.
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Indicative Module Content
Drug delivery systems and emerging technologies. Routes of administration: gastrointestinal, transdermal, parenteral, ocular, pulmonary, buccal, intranasal.
Modified release systems, drug targeting, microencapsulation and extrusion/spheronisation techniques, multiple and self emulsifying systems, oro-dispersibles.
Quality of biological products including vaccines and blood determinations.
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Pharmaceutical experimental design: Factorial design; optimisation techniques.
Indicative Student Workload
Contact Hours
| Full Time | Assessment
| 2 | Coursework
| 24 | Lectures
| 25 |
Directed Study
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| 49 |
Private Study
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| 50 |
Mode of Delivery
Lectures (including delivery by external industrialists), coursework (including a project) and directed study.
Assessment Plan
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Learning Outcomes Assessed
| | Component 1 | 1,2,3
| | Component 2 | 4,5
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Component 2. Assessed by a report and participation during the project work.
Component 1. A 2 hour written examination consisting of essay type questions is held at the end of the module
Indicative Bibliography
| 1. | *ALLEN, L.V., POPOVICH, N.G. and ANSEL, H.C., 2004. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. 8th ed. Philadelphia: Lippincott Williams & Wilkins.
| | 2. | ARMSTRONG, N.A. and JAMES, K.C., 1996. Pharmaceutical Expermental Design and Interpretation. London: Taylor and Francis.
| | 3. | *AULTON, M.E., ed. 2007. Aulton's Pharmaceutics: The Design and Manufacture of Medicines. 3rd ed. London: Churchill Livingstone.
| | 4. | SINKO, PATRICK J., 2006. Martin's Physical Pharmacy and Pharmaceutical Sciences. 5th ed. Lippincott Williams & Wilkins.
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