Module Database Search
| MODULE DESCRIPTOR | |||
|---|---|---|---|
| Module Title | |||
| Biomolecular Pharmacy | |||
| Reference | PH2131 | Version | 6 |
| Created | August 2021 | SCQF Level | SCQF 8 |
| Approved | March 2013 | SCQF Points | 30 |
| Amended | August 2021 | ECTS Points | 15 |
| Aims of Module | |||
|---|---|---|---|
| To develop an understanding of the structure, properties and actions of proteins, lipids and nucleic acids in the context of metabolism, disease and therapeutic targets and to appreciate the origins, properties and actions of drugs. | |||
| Learning Outcomes for Module | |
|---|---|
| On completion of this module, students are expected to be able to: | |
| 1 | Describe the structure, function and synthesis of cellular macromolecules including nucleic acids, proteins, lipids and carbohydrates; the processes of intermediate and xenobiotic metabolism and causes, symptoms and management strategies for selected inborn metabolic errors. |
| 2 | Discuss the origins, structures and properties of pharmacologically important compounds and apply the principles of rational drug design to selected classes of drugs. |
| 3 | Manipulate, interpret and evaluate experimental data. |
| 4 | Report procedures for the synthesis, extraction, isolation, characterisation and/or quantification of molecules of biological importance. |
| Indicative Module Content |
|---|
| Topics include: Structure, function, synthesis and metabolism of biomolecules including DNA, lipids and proteins. Enzymology: properties, mechanism of catalysis, regulation and kinetic analysis. Intermediate metabolism including glycolysis, tricarboxylic acid cycle and electron transport chain. Inborn errors of metabolism addressing causes and current and future therapeutic strategies. Drug discovery, drug targeting, mechanisms of drug action and the processes of xenobiotic metabolism. |
| Module Delivery |
|---|
| Lectures, coursework sessions (individual and group practicals, tutorials, PCCAL and online activities) and directed study activities (including participation in online forums discussing case studies, problem solving exercises, Articulate quizzes and directed reading). |
| Indicative Student Workload | Full Time | Part Time |
|---|---|---|
| Contact Hours | 178 | 178 |
| Non-Contact Hours | 122 | 122 |
| Placement/Work-Based Learning Experience [Notional] Hours | N/A | N/A |
| TOTAL | 300 | 300 |
| Actual Placement hours for professional, statutory or regulatory body |
| ASSESSMENT PLAN | |||||
|---|---|---|---|---|---|
| If a major/minor model is used and box is ticked, % weightings below are indicative only. | |||||
| Component 1 | |||||
| Type: | Examination | Weighting: | 85% | Outcomes Assessed: | 1, 2 |
| Description: | A 2 hour paper comprising multiple choice and short-answer type questions. | ||||
| Component 2 | |||||
| Type: | Coursework | Weighting: | 0% | Outcomes Assessed: | 3 |
| Description: | Competency test based on semester 1 coursework. | ||||
| Component 3 | |||||
| Type: | Coursework | Weighting: | 15% | Outcomes Assessed: | 4 |
| Description: | A laboratory report. | ||||
| MODULE PERFORMANCE DESCRIPTOR | |
|---|---|
| Explanatory Text | |
| The first grade represents Component 1 (EX1) weighted as major and the second grade, Component 3 (CW2), weighted as minor. Component 2 (CW1) is pass/unsuccessful. A minimum of Grade D or better is required to pass the module. Non-submission of either component will result in an NS grade | |
| Module Grade | Minimum Requirements to achieve Module Grade: |
| A | AA,AB,AC and a Pass in CW1. |
| B | BA,BB,BC,BD,AD,CA and a Pass in CW1. |
| C | CB,CC,CD,DA,DB and a Pass in CW1. |
| D | DC,DD and a Pass in CW1. |
| E | EA,EB,EC,ED,EE,EF,AE,BE,CE,DE,AF,BF,CF,DF,FA,FB,FC and a Pass in CW1. |
| F | FD,FE,FF and/or an unsuccessful attempt (i.e. Fail) in CW1. |
| NS | Non-submission of work by published deadline or non-attendance for examination |
| Module Requirements | |
|---|---|
| Prerequisites for Module | Successful completion of MPharm stage 1 or equivalent. |
| Corequisites for module | None. |
| Precluded Modules | None. |
| INDICATIVE BIBLIOGRAPHY | |
|---|---|
| 1 | GIBSON, G.G. and SKETT, P. An Introduction to Drug Metabolism. Current edition. Cheltenham: Nelson Thornes, UK. |
| 2 | COLEMAN, M,D., Human Drug Metabolism: An Introduction. Electronic resource. Hoboken, NJ: John Wiley & Sons. |
| 3 | PEET, A. Marks' Basic Medical Biochemistry. Current edition. Philadelphia: Lippincott Williams and Wilkins. |
| 4 | PARTICK, G.L., An Introduction to Medicinal Chemistry. Current edition. Oxford: Oxford University Press. |
| 5 | BRUICE, P.Y., Essential Organic Chemistry. Current edition. London: Pearson Education Ltd. |
| 6 | McMURRY, J. Organic Chemistry. Current edition. Pacific Grove, Ca: Brookes and Cole. |