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Module Title
Dosage Form Design

Keywords
biopharmaceutics, formulation, dosage forms, tablet technology, extemporaneous dispensing

ReferencePH2017
SCQF LevelSCQF 8
SCQF Points30
ECTS Points15
CreatedApril 2003
ApprovedAugust 2003
AmendedJuly 2006
Version No.3

Prerequisites for Module

Successful completion of module PH1013.

Corequisite Modules

None.

Precluded Modules

None.

Aims of Module

To provide the student with appropriate knowledge and skills to apply basic physicochemical principles and preformulation information to the design and production of stable pharmaceutical dosage forms.

Learning Outcomes for Module

On completion of this module, students are expected to be able to:

1. discuss the principles of biopharmaceutics.
2. critically evaluate the design, manufacture and efficacy of various drug dosage forms.
3. demonstrate competence in pharmaceutical calculations as necessary for the extemporaneous preparation of medicines.
4. demonstrate competence in the design of stable formulations and the preparation of extemporaneously prepared medicines.

Indicative Module Content

Biopharmaceutics: physiological, physicochemical and dosage form factors influencing drug absorption.
Dosage forms: the formulation and production of, drug release and bioavailability from certain dosage forms.
Instability and incompatibility in medicines: formulation techniques to minimise these.
Extemporaneous medicines: the formulation and compounding of extemporaneously prepared medicines.

Indicative Student Workload

Contact Hours

Full Time
Lectures
40
Coursework
36
Assessment
7

Directed Study

 

100

Private Study

 

117

Mode of Delivery

Lectures, practical laboratory coursework (including the extemporaneous preparation of medicines) and directed study

Assessment Plan

Learning Outcomes Assessed
Component 1 1,2,3
Component 2 2,3,4

Examination: A 2 hour paper 50% Section A 50% Section B. This examination contributes 70% towards the final Modular Grade.

Coursework:This will contribute 30% towards the final Modular Grade. A multiple choice open book test in week 34 will contribute 30% and a practical skills test will contribute 70%.

Indicative Bibliography

1.*AULTON, M., (ed)., 2002. Pharmaceutics: The Science of Dosage Form Design. 2nd ed. London: Churchill Livingstone.
* Recommended purchase
2.LUND, W., 1994. The Pharmaceutical Codex: Principles and Practice of Pharmaceutics. 12th ed. London: The Pharmaceutical Press.
3.FLORENCE, A.T. AND ATTWOOD, D., (eds)., 2006. Physicochemical Principles of Pharmacy. 4th ed. London: Pharmaceutical Press.
4.*WINFIELD, A. AND RICHARDS, M., (eds)., 2004. Pharmaceutical Practice. 3rd ed. London: Churchill Livingstone.
* Recommended purchase
5.Allen, L.V., Popovich N.G. and Ansel H.C., 2006. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. 8th Ed. Philadelphia: Lippincott Williams and Wilkins



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