Prerequisites for Module
Successful completion of module PH1013.
Corequisite Modules
None.
Precluded Modules
None.
Aims of Module
To provide the student with appropriate knowledge and skills to apply basic physicochemical principles and preformulation information to the design and production of stable pharmaceutical dosage forms.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1. |
discuss the principles of biopharmaceutics.
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2. |
critically evaluate the design, manufacture and efficacy of various drug dosage forms.
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3. |
demonstrate competence in pharmaceutical calculations as necessary for the extemporaneous preparation of medicines.
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4. |
demonstrate competence in the design of stable formulations and the preparation of extemporaneously prepared medicines.
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Indicative Module Content
Biopharmaceutics: physiological, physicochemical and dosage form factors influencing drug absorption. Dosage forms: the formulation and production of, drug release and bioavailability from certain dosage forms. Instability and incompatibility in medicines: formulation techniques to minimise these. Extemporaneous medicines: the formulation and compounding of extemporaneously prepared medicines.
Indicative Student Workload
Contact Hours
| Full Time | Lectures
| 40 | Coursework
| 36 | Assessment
| 7 | Directed Study
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| 100 | Private Study
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| 117 |
| Mode of Delivery
Lectures, practical laboratory coursework (including the extemporaneous preparation of medicines) and directed study
Assessment Plan
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Learning Outcomes Assessed
| Component 1 | 1,2,3
| Component 2 | 2,3,4
| Examination: A 2 hour paper 50% Section A 50% Section B. This examination contributes 70% towards the final Modular Grade.
Coursework:This will contribute 30% towards the final Modular Grade. A multiple choice open book test in week 34 will contribute 30% and a practical skills test will contribute 70%.
Indicative Bibliography
1. | *AULTON, M., (ed)., 2002. Pharmaceutics: The Science of Dosage Form Design. 2nd ed. London: Churchill Livingstone. * Recommended purchase
| 2. | LUND, W., 1994. The Pharmaceutical Codex: Principles and Practice of Pharmaceutics. 12th ed. London: The Pharmaceutical Press.
| 3. | FLORENCE, A.T. AND ATTWOOD, D., (eds)., 2006. Physicochemical Principles of Pharmacy. 4th ed. London: Pharmaceutical Press.
| 4. | *WINFIELD, A. AND RICHARDS, M., (eds)., 2004. Pharmaceutical Practice. 3rd ed. London: Churchill Livingstone. * Recommended purchase
| 5. | Allen, L.V., Popovich N.G. and Ansel H.C., 2006. Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems. 8th Ed. Philadelphia: Lippincott Williams and Wilkins
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