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MODULE DESCRIPTOR
Module Title
Pharmaceutical Chemistry
Reference PH1135 Version 3
Created August 2021 SCQF Level SCQF 7
Approved July 2017 SCQF Points 45
Amended August 2021 ECTS Points 22.5

Aims of Module
To provide an introduction to medicinal chemistry appropriate for the study and understanding of structures, properties and behaviours of molecules as applied to and in the context of pharmaceutical sciences.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Demonstrate a knowledge of selected aspects of medicinal chemistry which would include an understanding of the origins, structures, properties and behaviours of molecules within the context of pharmaceutical sciences, including drugs, excipients and receptors at a molecular level.
2 Demonstrate a knowledge of procedures used, problem solving and reporting of data in practical medicinal chemistry.

Indicative Module Content
Structure of molecules: electron configuration, orbitals, bonding, hybridisation, intermolecular forces, stereochemistry. Properties of solids, liquids & gases. Functional Groups: aliphatic, aromatic, heteroaromatic; reaction types. Bio Macromolecules: nucleic acids, proteins, carbohydrates, lipids. Origin of drugs: pharmacognosy, natural products. Drug structure, function, action, Lipinski's Rules. Basic laboratory skills in practical medicinal and pharmaceutical chemistry.

Module Delivery
This is a lecture based module supplemented with formative quizzes, tutorials, practical laboratory classes and guided reading.

Indicative Student Workload Full Time Part Time
Contact Hours 107 N/A
Non-Contact Hours 343 N/A
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 450 N/A
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Examination Weighting: 70% Outcomes Assessed: 1
Description: Closed book written examination
Component 2
Type: Coursework Weighting: 30% Outcomes Assessed: 2
Description: An individual written laboratory report

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
The first grade represents Component 1 (EX1) weighted as major and the second, Component 2 (CW1), weighted as minor. A minimum module grade of D is required for a pass. Non-submission of either component will result in an NS grade.
Module Grade Minimum Requirements to achieve Module Grade:
A AA,AB
B AC,AD,BA,BB,BC,CA
C BD,CB,CC,CD,DA,DB
D DC,DD,
E AE,BE,CE,DE,EE,EA,EB,EC,ED,AF,BF,CF,DF,
F FA,FB,FC,FD,FE,FF,EF
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module None, in addition to course requirements.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 BARBER, J. and ROSTON, C. Pharmaceutical Chemistry. Current Edition. Oxford University Press.
2 PATRICK, G. An Introduction to Medicinal Chemistry. Current Edition. Oxford University Press.
3 KOTZ, J.C., TREICHEL, P.M., TOWNSEND, J. AND TREICHEL, D. Chemistry and Chemical Reactivity. Current Edition, Thomson-Brookes/Cole.
4 CAIRNS, D. Essentials of Pharmaceutical Chemistry. Current Edition. Pharmaceutical Press.
5 LOUDON, G.M., 2016. Organic Chemistry. Sixth Edition. Oxford: Oxford University Press.
6 LOUDON, G.M. Organic Chemistry. Current Edition. Oxford University Press.


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