Module Title
Introduction To Medicinal Chemistry
Keywords
Atomic structure, spectroscopy, organic functional groups, pharmacognosy, natural products, stereochemistry, drug structure. |
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Prerequisites for Module
None, in addition to course requirements.
Corequisite Modules
None.
Precluded Modules
None.
Aims of Module
To provide an introduction to the chemical sciences appropriate for the study and understanding of structures, properties and behaviour of drugs at the molecular level.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Show a knowledge of selected aspects of chemical science appropriate for the study and understanding of the origins, structures, properties and behaviour of drugs.
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| 2. |
Demonstrate a knowledge of procedures used, problem solving and reporting skills in practical pharmaceutical and medicinal chemistry.
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Indicative Module Content
The application of various aspects of chemistry in order to understand the fundamental properties of drugs at molecular level.
| Topics include: fundamental atomic theory, quantum chemistry introducing the concept of atomic orbitals; bonding processes including molecular orbital theory; orbital hybridisation; properties and functions of simple organic pharmaceuticals; an introduction to pharmacognosy and drug discovery from natural products; application of stereochemistry to pharmaceutical and biochemical processes; a study of selected functional groups to predict the properties of drug molecules; basic laboratory skills in practical medicinal and pharmaceutical chemistry.
Indicative Student Workload
Contact Hours
| Full Time | Coursework
| 52 | Lectures
| 44 | Supervised assessment
| 2 |
Directed Study
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| 108 |
Private Study
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| 94 |
Mode of Delivery
Lectures, coursework sessions (both laboratory and non-laboratory based) and directed study.
Assessment Plan
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Learning Outcomes Assessed
| | Component 1 | 1
| | Component 2 | 2
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Component 2 is a written coursework report.
Component 1 is a 2 hour examination consisting of multiple choice and short answer questions.
Indicative Bibliography
| 1. | KOTZ,J.C., TREICHEL, P. and WEAVER, G.C. Chemistry and Chemical Reactivity. Current edition. Belmont, CA: Thomson, Brokes, Cole
| | 2. | EVANS, W.C. Trease and Evan's Pharmacognosy. Current edition. London:Saunders
| | 3. | LOUDON, G.M., Organic Chemistry. Current edition. Oxford: Oxford University Press
| | 4. | SOLOMONS, T.W. and FRYHLE, C. Organic Chemistry. Current edition. Hoboken, N.J.: Wiley
| | 5. | PATRICK, G. An Introduction to Medicinal Chemistry. Current edition. Oxford: Oxford Universty Press
| | 6. | CAIRNS, D. Essentials of Pharmaceutical Chemistry. Current edition. London: Pharmaceutical Press
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