Module Title
Introduction To Medicinal Chemistry
Keywords
Atomic structure, spectroscopy, organic functional groups, pharmacognosy, natural products, stereochemistry, drug structure |
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Prerequisites for Module
None, in addition to course requirements.
Corequisite Modules
None
Precluded Modules
None
Aims of Module
To provide an introduction to the chemical sciences appropriate for the study and understanding of structures, properties and behaviour of drugs at the molecular level.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Demonstrate an understanding of atomic theory, bonding and basic spectroscopy.
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| 2. |
Demonstrate an understanding of the importance of stereochemistry in drug function.
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| 3. |
Apply basic pharmacognosy in drug discovery and in the production of drugs from natural sources.
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| 4. |
Understand the properties and functions of selected drug compounds based on their structure.
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| 5. |
Demonstrate a knowledge of procedures used in and problem solving skills in practical pharmaceutical and medicinal chemistry.
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Indicative Module Content
Fundamental atomic theory, quantum chemistry introducing the concept of atomic orbitals. Bonding processes including molecular orbital theory. Orbital hybridisation. Spectroscopy. Properties and functions of simple organic pharmaceuticals. An introduction to pharmacognosy and drug discovery from natural products. Application of stereochemistry to pharmaceutical and biochemical processes. A study of selected organic functional groups to predict the properties of drug molecules. Basic laboratory skills in practical medicinal and pharmaceutical chemistry.
| Indicative Student Workload
Contact Hours
| Full Time | Coursework
| 44 | Lectures
| 46 | Supervised assessment
| 6 |
Directed Study
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| 106 |
Private Study
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| 98 |
Mode of Delivery
Lectures, coursework sessions (both laboratory and non-laboratory based) and directed studies.
Assessment Plan
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Learning Outcomes Assessed
| | Component 1 | 1,2,3,4
| | Component 2 | 5
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Compnent 2 is assessed by two equally weighted coursework tests (one in each semester).
Component 1 is assessed by a 2 hour examination consisting of multiple choice and short answer questions.
Indicative Bibliography
| 1. | KOTZ,J.C., TREICHEL, P. and WEAVER, G.C.,2009. Chemistry and Chemical Reactivity. 7th ed. Belmont, CA: Thomson, Brokes, Cole
| | 2. | EVANS, W.C. 2001. Trease and Evan's Pharmacognosy. 15th ed. London:Saunders
| | 3. | LOUDON, G.M., 2005. Organic Chemistry. 4th ed., Oxford:Oxford University Press
| | 4. | SOLOMONS, T.W. and FRYHLE, C., 2008. Organic Chemistry. 9th ed. Hoboken, N.J.: Wiley
| | 5. | PATRICK, G., 2009. An Introduction to Medicinal Chemistry. 4th ed., Oxford: Oxford Universty Press
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