Module Database Search
| MODULE DESCRIPTOR | |||
|---|---|---|---|
| Module Title | |||
| Drug Analysis And Toxicology | |||
| Reference | ASM032 | Version | 2 |
| Created | August 2021 | SCQF Level | SCQF 11 |
| Approved | February 2018 | SCQF Points | 30 |
| Amended | August 2021 | ECTS Points | 15 |
| Aims of Module | |||
|---|---|---|---|
| To enable the students to critically evaluate the principles, applications and limitations of instrumental analysis in Drug Analysis and Toxicology and to select and implement a range of appropriate analytical techniques to solve a given analytical problem. | |||
| Learning Outcomes for Module | |
|---|---|
| On completion of this module, students are expected to be able to: | |
| 1 | Critically review the formulation and dosage forms of abused and common pharmaceutical drugs and evaluate instrumental methods for their analysis. |
| 2 | Critically appraise in a confident and professional manner; the sources, route, distribution and excretion of toxins or poisons. |
| 3 | Critically review and plan proposed analytical work on a problem involving a toxin or an abused or common pharmaceutical drug. Carry out the work as a member of a group, interacting confidently and effectively, demonstrating appropriate negotiating and leadership skills and present the findings in a professional setting. |
| Indicative Module Content |
|---|
| Drug screening and confirmation. Analytical procedures for the determination of drugs of abuse in biological matrices e.g. blood, serum, plasma, saliva, urine etc. Structure elucidation, Pharmaceutical drug analysis, drug formulation, use of general pharmaceutical monographs for formulated preparations. Measuring toxicology: LD50, exposure limits, thresholds, reversibility, sensitivity. Toxicokinetics: absorption, distribution, metabolism and excretion. Solution of an analytical problem appropriate to Drug Analysis or Toxicology requiring a combination of Laboratory techniques. |
| Module Delivery |
|---|
| Full-time and Part-time; the module is delivered by formal lectures and some external speakers. Mandatory attendance for 5 days of laboratory work as part of a designated group solving a drug analysis or toxicology problem. |
| Indicative Student Workload | Full Time | Part Time |
|---|---|---|
| Contact Hours | 70 | 50 |
| Non-Contact Hours | 230 | 250 |
| Placement/Work-Based Learning Experience [Notional] Hours | N/A | N/A |
| TOTAL | 300 | 300 |
| Actual Placement hours for professional, statutory or regulatory body |
| ASSESSMENT PLAN | |||||
|---|---|---|---|---|---|
| If a major/minor model is used and box is ticked, % weightings below are indicative only. | |||||
| Component 1 | |||||
| Type: | Practical Exam | Weighting: | 50% | Outcomes Assessed: | 3 |
| Description: | Demonstrate competent laboratory planning & analysis of an abused or common pharmaceutical drug and individual performance in a PowerPoint presentation. | ||||
| Component 2 | |||||
| Type: | Coursework | Weighting: | 50% | Outcomes Assessed: | 1, 2 |
| Description: | Critical review and assessment of analytical techniques for the analysis of a given abused or common pharmaceutical drug or toxin. Consideration of pertinent formulation, pharmacokinetics, regulations and legislation will be emphasised. | ||||
| MODULE PERFORMANCE DESCRIPTOR | |
|---|---|
| Explanatory Text | |
| The first grade represents Component 1 (PE1) equally weighted with the second, Component 2 (CW2). A minimum of Module Grade D is required to pass the module, with compensation of grade E in Component 1 or Component 2 permitted. Non-submission of either component will result in an NS grade. | |
| Module Grade | Minimum Requirements to achieve Module Grade: |
| A | AA, AB, BA |
| B | AC, AD, BB, BC, CA, CB, DA |
| C | AE, BD, BE, CC, CD, DB, DC, EA, EB |
| D | CE, DD, DE, EC, ED |
| E | AF, BF, CF, DF, EF, FA, FB, FC, FD, FE |
| F | FF |
| NS | Non-submission of work by published deadline or non-attendance for examination |
| Module Requirements | |
|---|---|
| Prerequisites for Module | None. |
| Corequisites for module | None. |
| Precluded Modules | None. |
| INDICATIVE BIBLIOGRAPHY | |
|---|---|
| 1 | AULTON, M.E., Current edition. Pharmaceutics, The Design and Manufacture of Medicines. Churchill Livingstone Elsevier. |
| 2 | WATSON, D.G., Current edition. Pharmaceutical Analysis. Churchill Livingstone Elsevier. |
| 3 | ANSEL, H.C., Current edition. Pharmaceutical Dosage Forms and Drug Delivery Systems. Wolters Kluwer Health. |
| 4 | CREAN, A., Current edition. The physiochemical basis of Pharmaceuticals. Oxford University Press. |
| 5 | SKOOG, W. CROUCH, S. WEST, D and HOLLER, F. Current edition. Skoog and West. Fundamentals of Analytical Chemistry. Cengage Learning |