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MODULE DESCRIPTOR
Module Title
Extended Elective Studies (Drug Analysis and Toxicology)
Reference ASM015 Version 5
Created August 2017 SCQF Level SCQF 11
Approved June 2008 SCQF Points 15
Amended September 2017 ECTS Points 7.5

Aims of Module
To enable the students to evaluate the principles, application and limitations of instrumental analysis in drug analysis and toxicology.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Demonstrate a critical understanding of formulation and dosage forms and justify the principles and application of drug analysis and toxicology.
2 Discuss clearly and confidently the methods used for the determination of substances of abuse, common pharmaceutical drugs and preparations.
3 Discuss and critically appraise in a confident and professional manner the sources, route, distribution and excretion of toxins or poisons.
4 Critically evaluate and propose suitable methodologies for the determination of a given drug.

Indicative Module Content
Drug screening and confirmation. Analytical procedures for the determination of drugs of abuse in biological matrices e.g. blood, serum, plasma, saliva, urine etc. Structure elucidation, Pharmaceutical drug analysis drug formulation, use of general pharmaceutical monographs for formulated preparations. Measuring toxicology: LD50, exposure limits, thresholds, reversibility, sensitivity. Toxicokinetics: absorption, distribution, metabolism and excretion.

Module Delivery
The module is delivered mostly by formal lectures with some external specialist speakers.

Indicative Student Workload Full Time Part Time
Contact Hours 50 50
Non-Contact Hours 100 100
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 150 150
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Coursework Weighting: 100% Outcomes Assessed: 1, 2, 3, 4
Description: A critical review of the literature to determine and report a method for the analysis of a given substance of abuse or common pharmaceutical drug in a biological matrix. Consideration of the formulation, dose and pharmacokinetics of the drug will be made evident.

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
This module is assessed according to the assessment Plan. To pass this module, candidates must achieve a Module Grade of D or better.
Module Grade Minimum Requirements to achieve Module Grade:
A Final mark of 70% or greater
B Final mark between 60-69%
C Final mark between 50-59%
D Final mark between 40-49%
E MARGINAL FAIL. Final mark between 35-39%
F FAIL. Final mark is less than 35%
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module In addition to course entry requirements, students must be familiar with the basic principles of chromatography, spectroscopy, electrochemistry and biochemistry.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 Aulton, M.E., Pharmaceutics, The Design and Manufacture of Medicines. Current Edition. Churchill Livingstone Elsevier.
2 Watson, D.G.,Pharmaceutical Analysis. Current Edition. Churchill Livingstone Elsevier.
3 Ansel, H.C., Pharmaceutical Dosage Forms and Drug Delivery Systems. Current Edition. Wolters Kluwer Health.
4 Crean, A., 2009. The physiochemical basis of Pharmaceuticals. 1st Ed. Oxford University Press.

 

Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781