Prerequisites for Module
Population Genetics (AS4020 or equivalent)
Corequisite Modules
Refer to Definitive Course Document.
Precluded Modules
Refer to Definitive Course Document.
Aims of Module
To provide students with the concepts and principles underlying the forensic analysis of DNA.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1. |
Describe DNA profiling systems and the technical differences underlying each method in current use.
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2. |
Explain the procedures for the collection of biological samples for analysis.
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3. |
Make effective use of databases for information on allele frequencies.
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4. |
Statistically evaluate and interpret profiling data and discuss the limitations and problems associated with DNA profiling.
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Indicative Module Content
Bais of nucleic acid typing systems. DNA polymorphisms used in forensic laboratories. Procedures used for forensic DNA fingerprinting. Sources of DNA samples for analysis. DNA extraction and preparation procedures. Methods of analysis. Interpretation of data. Problems associated with interpretation of data (Bayes' Rule): genetic-based and laboratory-based.
| Indicative Student Workload
Contact Hours
| Full Time | Lectures
| 30 | Tutorials/Seminars
| 10 | Directed Study
| | Directed Study
| 40 | Private Study
| | Private Study
| 70 |
Mode of Delivery
The module comprises lectures supplemented with tutorials, demonstrations and guided reading. Students will undertake a short course on statistics (Bayes' Rule).
Assessment Plan
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Learning Outcomes Assessed
| Coursework | 3,4
| Examination | 1,2
| The coursework will involve researching databases and statistically evaluating and critically presenting DNA profiling data.
Indicative Bibliography
1. | EVETT, I.W. AND WEIR, B.S., 1998. Interpreting DNA Evidence. Statistical genetics for Forensic Scientists. Sunderland MA:Sinauer Associates.
| 2. | AITKEN, C.G.G., 1995. Statistics and the evaluation of evidence for Forensic Scientists. J Wiley and Sons.
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