Prerequisites for Module
AS3013 and AS3018/AS3068 or equivalent
Corequisite Modules
None.
Precluded Modules
None.
Aims of Module
Understand the principles and practice of DNA Profiling
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Explain in-depth the biochemistry of DNA profiling.
|
| 2. |
Discuss the use of genetic variability in human and animal identification.
|
| 3. |
Determine the optimal method for DNA profiling in a variety of circumstances.
|
Indicative Module Content
History of DNA analysis, DNA structure and intron variation. DNA sample handing and extraction, contamination precautions. Location of STRs, VNTRs and SNPs. The advantages and disadvantages of each system in profiling. Y chromosome STRs, mitochondrial DNA and multiplexing of probes.
Species and sex identification for wildlife forensic and conservation biology applications.
Indicative Student Workload
Contact Hours
| Full Time | Laboratory Work
| 20 | Problem Solving
| 5 | Tutorials
| 4 | lectures
| 20 |
Directed Study
| |
| 55 |
Private Study
| |
| 46 |
| Mode of Delivery
The course will be delivered through formal lectures and tutorials together with practical laboratory exercises and problem solving sessions.
Assessment Plan
|
Learning Outcomes Assessed
| | Component 1 | 2,3
| | Component 2 | 1
|
The assessment for this component will an essay.
The assessment for this component will be a closed book exam.
Indicative Bibliography
| 1. | BROWN, T.A. 2006. Gene Cloning and DNA Analysis: An Introduction. 5th ed. Blackwell.
| | 2. | DALE, J.W. and VON SCHANTZ, M., 2007. From Genes to Genomes. Concepts and Applications of DNA Technology. 2nd ed. John Wiley.
| | 3. | JAMES, S.H. and NORDBY, J.J., 2005. Forensic Science: An Introduction to Scientific and Investigative Techniques. 2nd ed. CRC Press.
| | 4. | RUDIN, N. and INMAN, K., 2002. An Introduction to Forensic DNA Analysis. CRC Press.
| | 5. | BUTLER, J.M., 2010. Fundamentals of Forensic DNA Typing. 3rd ed Academic Press.
|
|