Prerequisites for Module
The student should be familiar with the fundamental principles of biochemistry, microbiology and molecular technology (refs. AS2003, AS2056, AS3004 and AS3055 or equivalent)
Corequisite Modules
Refer to Definitive Course Document.
Precluded Modules
Refer to Definitive Course Document.
Aims of Module
To provide the student with the ability to assess the enabling technologies which contribute to industrial biotechnological processes, and to appreciate the importance of biotechnology to society.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Explain the cellular and molecular aspects of bioproduction technologies.
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| 2. |
Describe the conditions and processes associated with industrial synthesis and recovery of bioproducts.
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| 3. |
Discuss the applications of biotechnology and critically assess the importance of biotechnological processes and products for medicine, agriculture and the food industry.
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Indicative Module Content
Developments in bioprocess technology; consideration of biocatalyst, production environment and downstream processing; fermentation technology; product recovery and purification; bioconversions. Genetic engineering; selection of producer strain; genetic manipulation of producer; cloning technology for heterologous gene expression; recombinant expression systems; prokaryotic and eukaryotic microbial hosts; bacteria, fungi, yeasts, plants, insect and mammalian cell culture; hybridoma technology; antibody engineering; plant biotechnology.
| Indicative Student Workload
Contact Hours
| Full Time | Lectures
| 25 | Tutorials/Seminars
| 10 | Supervised Assessments
| 10 |
Directed Study
| | Directed Study
| 45 |
Private Study
| | Private Study
| 60 |
Mode of Delivery
A combined approach utilising formal lectures, directed reading and tutorials will form the basis for delivery of this module.
Assessment Plan
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Learning Outcomes Assessed
| | Coursework | 3
| | Examination | 1,2,3
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The examination will consist of extended response questions.
Indicative Bibliography
| 1. | S B Primrose et al, Principles of Gene Manipulation - an Introduction to Genetic Engineering (6th Edition) Blackwell Publishing (2002).
| | 2. | B R Glick & J J Pasternak, Molecular Biotechnology (3rd Edition) ASM Press (2002).
| | 3. | L M Houdebine, Animal Transgenesis and Cloning (1st Edition) Wiley (2003).
| | 4. | A Slater et al, Plant Biotechnology (1st Edition) Oxford University Press (2003).
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