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MODULE DESCRIPTOR
Module Title
Clinical Immunology
Reference AS3901 Version 4
Created August 2021 SCQF Level SCQF 9
Approved May 2011 SCQF Points 15
Amended September 2021 ECTS Points 7.5

Aims of Module
To provide students with the ability to discuss the molecular and cellular basis of diseases affecting the immune system, and the applications of immunological techniques designed to diagnose and monitor them.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Discuss lymphocyte activation and control, and the interaction of the immune system with antigen.
2 Explain the immunology of hypersensitivity, autoimmunity, immunodeficiency, transplantation and cancer.
3 Explain the features and applications of immunoassays in the diagnosis and monitoring of diseases affecting the immune system.

Indicative Module Content
Lymphocyte Activation & Control: first and second signals, accessory molecules, soluble immunoregulators (cytokines, interleukins, chemokines).Defence against Infection: vaccination, subversion by pathogens, superantigens. Hypersensitivity : types I to V. Autoimmunity: MHC, rheumatological (SLE, RA, autoantibodies) and kidney(Goodpastures) and organ-specific (thyroid, coeliac, pernicious anaemia, diabetes) diseases. Immunodeficiency: Complement, primary (T & B & NK cell) and secondary (HIV). Transplantation: rejection, solid organs, bone marrow. Cancer : tumour antigens, evasion. Immunoassays: haemagglutination, RIA, ELISA, tissue typing, functional assays.

Module Delivery
This is a lecture based module supplemented by tutorials and group discussions.

Indicative Student Workload Full Time Part Time
Contact Hours 40 N/A
Non-Contact Hours 110 N/A
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 150 N/A
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Examination Weighting: 70% Outcomes Assessed: 2, 3
Description: Extended response questions
Component 2
Type: Coursework Weighting: 30% Outcomes Assessed: 1
Description: Problem solving exercise

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
The first grade represents Component 1 (EX1) weighted as major and the second, Component 2 (CW1), weighted as minor. A minimum of Module Grade D is required to pass the module, with compensation of grade E in in Component 1 or Component 2 permitted. Non-submission of either component will result in an NS grade.
Module Grade Minimum Requirements to achieve Module Grade:
A AA, AB
B AC, AD, AE, BA, BB, BC, CA
C BD, BE, CB, CC, CD, DA, DB
D CE, DC, DD, DE, EA, EB, EC
E AF, BF, CF, DF, ED, EE, EF, FA, FB, FC, FD
F FE, FF
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module Successful completion of Stage 2 of the course, or equivalent.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 HALL, A., SCOTT, C.,and BUCKLAND, M. Clinical Immunology. Current edition. Oxford University Press.
2 DELVES, P.J., MARTIN, S.J., BURTON, D.R and ROITT, I.M. Roitt's Essential Immunology. Current Edition. Wiley-Blackwell Publishing.


Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781