Module Title
Cell Pathology
Keywords
Integumentary, Skeletal, Muscular, Cardiovascular, Respiratory, Urinary and Digestive Systems |
|
Prerequisites for Module
The student will normally have completed modules AS1053 and AS2055 or their equivalents.
Corequisite Modules
Refer to Definitive Course Document.
Precluded Modules
Refer to Definitive Course Document.
Aims of Module
To provide the student with the ability to explain the techniques, methods and role of histopathology in the diagnosis of disease.
Learning Outcomes for Module
On completion of this module, students are expected to be able to:
| 1. |
Describe the preparation of histological and cytological specimens.
|
| 2. |
Explain the diagnostic value of specialised procedures such as histochemistry, immunocytochemistry and electron microscopy and their methodology.
|
| 3. |
REcognise the changes in cells and tissues brought about by disease.
|
Indicative Module Content
Organisation of a histopathology department and its value in the diagnostic process. Tissue Processing: fixation, dehydration, impregnation and embedding, specialised procedures. Tissue sectioning, principles of coloration and staining. Histochemistry: pigments, lipids, nucleic acids and enzymes. Image analysis.
Immunocytochemistry and its value, Use of tumour markers. Electron Microscopy: The structure on an electron microscope, organelle identification in electron micrographs.
| Cytopathology: screening programmes. Recognition of cell types and the changes brought about by disease, diagnostic cytopathology, recognition of cell types in respiratory specimens and body fluids, fine needle aspiration.
Histopathology: The general basis of disease, the changes in cells and tissues associated with inflammation, thrombosis, infarction and tumours.
Indicative Student Workload
Contact Hours
| Full Time | Lectures
| 40 | Tutorials/Seminars
| 10 | Supervised Assessments
| 2 | Demonstrations/Visits
| 5 |
Directed Study
| | Directed Study
| 18 |
Private Study
| | Private Study
| 75 |
Mode of Delivery
This is a lecture based course supplemented with tutorial sessions, case studies, practical demonstrations and visits to working laboratories.
Assessment Plan
|
Learning Outcomes Assessed
| | Coursework | 2,3
| | Examination | 1,2,3
|
The coursework will consist of problem-solving exercises.
The examination will consist mainly of extended response questions.
Indicative Bibliography
| 1. | J D Bancroft and A Stevens, Theory and Practice of Histological Techniques (4th Edition), Churchill Livingstone (1996).
| | 2. | W Gray (Ed.), Diagnostic Cytopathology (1st Edit) Churchill Livingstone (1995).
| | 3. | N Woolf, Cell Tissue and Disease (2nd Edit) Balliere Balliere Tindall (1986)
|
|
|