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MODULE DESCRIPTOR
Module Title
Human Biochemistry
Reference AS2502 Version 3
Created June 2022 SCQF Level SCQF 8
Approved February 2018 SCQF Points 15
Amended June 2022 ECTS Points 7.5

Aims of Module
To enable students to explain metabolic pathways, their regulation, and understand the biological significance of their products.

Learning Outcomes for Module
On completion of this module, students are expected to be able to:
1 Describe the nature and sequence of the biochemical reactions in the principal metabolic pathways of carbohydrates, lipids, nucleic acids and proteins.
2 Explain the biological significance and fates of the metabolic intermediates and end products of the principal human metabolic pathways.
3 Appreciate the major control sites in metabolic pathways, the mechanisms for their control and give an accurate and reasoned account of the integration of metabolism.
4 Explain selected disorders of metabolism in terms of molecular abnormalities and their metabolic consequences.

Indicative Module Content
Carbohydrate metabolism: glycolysis, physiological significance and cost of anaerobic and aerobic metabolism, the citric acid cycle. Gluconeogenesis, glycogenolysis, glycogen synthesis. Mechanisms of control of carbohydrate metabolism. Lipid metabolism: dietary lipids, catabolism of triacylglycerols and fatty acids. Biosynthesis of fatty acids. Control of fatty acid metabolism. Cholesterol synthesis, lipoprotein metabolism. Protein metabolism: protein turnover, hydrolysis of proteins, degradation of amino acids, urea cycle. Integration of metabolism: major control sites and junctions. Enzyme regulation, metabolic regulators, hormone regulators, induction and repression of enzyme synthesis. Metabolic adaptations and alterations in the fed and fasted state. Nucleotide biosynthesis and catabolism. Inherited metabolic diseases.

Module Delivery
This is a lecture based module supplemented with formative tests, question and answer sessions and guided reading.

Indicative Student Workload Full Time Part Time
Contact Hours 30 N/A
Non-Contact Hours 120 N/A
Placement/Work-Based Learning Experience [Notional] Hours N/A N/A
TOTAL 150 N/A
Actual Placement hours for professional, statutory or regulatory body    

ASSESSMENT PLAN
If a major/minor model is used and box is ticked, % weightings below are indicative only.
Component 1
Type: Examination Weighting: 100% Outcomes Assessed: 1, 2, 3, 4
Description: Closed book examination consisting of multiple choice questions.

MODULE PERFORMANCE DESCRIPTOR
Explanatory Text
Component 1 (EX1) comprises 100% of the module grade. A minimum of Grade D is required to pass the module.
Module Grade Minimum Requirements to achieve Module Grade:
A A
B B
C C
D D
E E
F F
NS Non-submission of work by published deadline or non-attendance for examination

Module Requirements
Prerequisites for Module Successful completion of Stage 1, or equivalent.
Corequisites for module None.
Precluded Modules None.

INDICATIVE BIBLIOGRAPHY
1 STRYER, L. Biochemistry. Current Edition. W H Freeman & Co. Ltd.
2 CHAMPE, P.C., et al Lippincott's Illustrated Reviews: Biochemistry, International Students Edition (Lippincott's Illustrated Reviews Series). Current Edition. Lippincott Williams and Wilkins.


Robert Gordon University, Garthdee House, Aberdeen, AB10 7QB, Scotland, UK: a Scottish charity, registration No. SC013781