Module Database Search
| MODULE DESCRIPTOR | |||
|---|---|---|---|
| Module Title | |||
| Human Biochemistry | |||
| Reference | AS2098 | Version | 5 |
| Created | February 2017 | SCQF Level | SCQF 8 |
| Approved | June 2002 | SCQF Points | 15 |
| Amended | August 2017 | ECTS Points | 7.5 |
| Aims of Module | |||
|---|---|---|---|
| To enable students to explain metabolic pathways, their regulation, and understand the biological significance of their products. | |||
| Learning Outcomes for Module | |
|---|---|
| On completion of this module, students are expected to be able to: | |
| 1 | Describe the nature and sequence of the biochemical reactions in the principal metabolic pathways of carbohydrates, lipids, nucleic acids and proteins. |
| 2 | Explain the biological significance and fates of the metabolic intermediates and end products of the principal human metabolic pathways. |
| 3 | Appreciate the major control sites in metabolic pathways, the mechanisms for their control and give an accurate and reasoned account of the integration of metabolism. |
| 4 | Explain selected disorders of metabolism in terms of molecular abnormalities and their metabolic consequences. |
| Indicative Module Content |
|---|
| Carbohydrate metabolism: glycolysis, physiological significance and cost of anaerobic and aerobic metabolism, the citric acid cycle. Gluconeogenesis, glycogenolysis, glycogen synthesis. Mechanisms of control of carbohydrate metabolism. Lipid metabolism: dietary lipids, catabolism of triacylglycerols and fatty acids. Biosynthesis of fatty acids. Control of fatty acid metabolism. Cholesterol synthesis, lipoprotein metabolism. Protein metabolism: protein turnover, hydrolysis of proteins, degradation of amino acids, urea cycle. Integration of metabolism: major control sites and junctions. Enzyme regulation, metabolic regulators, hormone regulators, induction and repression of enzyme synthesis. Metabolic adaptations and alterations in the fed and fasted state. Nucleotide biosynthesis and catabolism. Inherited metabolic diseases. |
| Module Delivery |
|---|
| This is a lecture based module supplemented with formative tests, question and answer sessions and guided reading. |
| Indicative Student Workload | Full Time | Part Time |
|---|---|---|
| Contact Hours | 30 | N/A |
| Non-Contact Hours | 120 | N/A |
| Placement/Work-Based Learning Experience [Notional] Hours | N/A | N/A |
| TOTAL | 150 | N/A |
| Actual Placement hours for professional, statutory or regulatory body |
| ASSESSMENT PLAN | |||||
|---|---|---|---|---|---|
| If a major/minor model is used and box is ticked, % weightings below are indicative only. | |||||
| Component 1 | |||||
| Type: | Examination | Weighting: | 70% | Outcomes Assessed: | 1, 2, 3 |
| Description: | Closed book examination (2h) consisting of essay and multiple choice questions. | ||||
| Component 2 | |||||
| Type: | Coursework | Weighting: | 30% | Outcomes Assessed: | 4 |
| Description: | Group presentation (normally comprising 3 class members) on a pre-selected inherited metabolic disorder. | ||||
| MODULE PERFORMANCE DESCRIPTOR | |
|---|---|
| Explanatory Text | |
| This module is assessed using the two components of assessment as detailed in the Assessment Plan. To pass this module, candidates must achieve a Module Grade D or better. | |
| Module Grade | Minimum Requirements to achieve Module Grade: |
| A | Final aggregate mark of 70% or greater and a minimum of 35% in C1 and C2 |
| B | Final aggregate mark of between 60-69% and a minimum of 35% in C1 and C2 |
| C | Final aggregate mark of between 50-59% and a minimum of 35% in C1 and C2 |
| D | Final aggregate mark of between 40-49% and a minimum of 35% in C1 and C2 |
| E | MARGINAL FAIL. Final aggregate of between 35-39% and a minimum of 35% in C1 and C2 |
| F | FAIL. A mark of less than 35% in either component |
| NS | Non-submission of work by published deadline or non-attendance for examination |
| Module Requirements | |
|---|---|
| Prerequisites for Module | Successful completion of Stage 1 Biomedical Science Programme, or equivalent. |
| Corequisites for module | None. |
| Precluded Modules | None. |
| INDICATIVE BIBLIOGRAPHY | |
|---|---|
| 1 | STRYER, L. Biochemistry. Current Edition. W H Freeman & Co. Ltd. |
| 2 | CHAMPE, P.C., HARVEY, R.A., FERRIER, D.R. Lippincott's Illustrated Reviews: Biochemistry, International Students Edition (Lippincott's Illustrated Reviews Series). Current Edition. Lippincott Williams and Wilkins. |
| 3 | NELSON, D.L. and COX, M.M. Lehninger Principles of Biochemistry. Current Edition. W. H. Freeman Ltd. |